治療ガイドライン

子宮体癌治療ガイドライン2006年版(英語版):(金原出版)

子宮体癌治療ガイドライン

Chapter 1 Overview of Guidelines (PDF/174KB)
Chapter 2 Initial Treatment (PDF/405KB)
Chapter 3 Postoperative Adjuvant Therapy (PDF/261KB)
Chapter 4 Post-treatment Follow-up (PDF/153KB)
Chapter 5 Treatment of Advanced and Recurrent Cancer (PDF/228KB)
Chapter 6 Fertility-Preserving Treatment (PDF/160KB)
Chapter 7 Atypical Endometrial Hyperplasia (PDF/118KB)
Reference (PDF/482KB)

目次

Chapter 1 Overview of Guidelines

Chapter 2 Initial Treatment

Overview
CQ01 :Which forms of hysterectomy are recommended for clinical stage I?
CQ02 :Which surgical techniques of hysterectomy are recommended for clinical stage II?
CQ03 :What is the significance of pelvic lymphadenectomy?
CQ04 :What are the benefits of para-aortic lymphadenectomy in addition to pelvic lymphadenectomy?
CQ05 :Does partial vaginectomy reduce the rate of vaginal stump recurrence?
CQ06 :Is ovarian preservation possible in young patients?
CQ07 :In surgical staging, inguinal lymph node metastases are often mentioned. Should inguinal lymph nodes be biopsied?
CQ08 :Is omentectomy necessary?
CQ09 :Is rapid intraoperative pathological diagnosis useful for the determination of histological type and degree of differentiation?
CQ10 :How should the degree of myometrial invasion be determined intraoperatively?
CQ11 :Is rapid intraoperative pathological diagnosis useful for the detection of lymph node metastasis?
CQ12 :Is positive peritoneal cytology an independent predictor of a poor prognosis?
CQ13 :Is rapid intraoperative peritoneal cytology necessary for determination of the best surgical technique?
CQ14 :Will endoscopic surgery become a standard surgical technique?
CQ15 :Can lymphadenectomy be omitted if sentinel node biopsy is performed?
CQ16 :Is radiatiotherapy useful for inoperable patients who are elderly or who have other medical conditions?

Chapter 3 Postoperative Adjuvant Therapy

Overview

I. Radiotherapy

Overview

CQ17 :Is postoperative whole-pelvis external-beam irradiation useful?
CQ18 :Is postoperative intracavitary irradiation of the vaginal stump useful?
CQ19 :Are postoperative irradiation of the para-aortic lymph node region and whole abdominal irradiation useful?
CQ20 :What are the contraindications for postoperative radiotherapy?

II. Chemotherapy and Hormone Therapy

Overview

CQ21 :Has the efficacy of postoperative adjuvant chemotherapy been confirmed?
CQ22 :Which regimens are recommended for postoperative adjuvant chemotherapy?
CQ23 :Is hormone therapy effective as postoperative adjuvant therapy?

Chapter 4 Post-treatment Follow-up

Overview
CQ24 :What intervals are recommended for post-treatment follow-up?
CQ25 :Is determination of serum CA125 and CA19-9 levels useful in post-treatment follow-up?
CQ26 :Are pelvic examination and vaginal vault smears useful in post-treatment follow-up?
CQ27 :Are plain chest radiography and other diagnostic imaging methods useful in post-treatment follow-up?

Chapter 5 Treatment of Advanced and Recurrent Cancer

Overview
CQ28 :When is surgery indicated for clinical stages III and IVa?
CQ29 :What are the therapeutic benefits of cytoreductive surgery for patients with macroscopic extrapelvic and intra-abdominal spread?
CQ30 :Are preoperative chemotherapy and radiotherapy useful?
CQ31 :When is surgery indicated for recurrent cancer?
CQ32 :Is chemotherapy useful for advanced and recurrent cancer?
CQ33 :Which regimens are recommended for chemotherapy in advanced and recurrent cancer?
CQ34 :Is radiotherapy useful for recurrent and inoperable advanced cancer?
CQ35 :Is progesterone therapy useful for advanced and recurrent cancer?

Chapter 6 Fertility-Preserving Treatment

Overview
CQ36 :Is progesterone therapy useful for patients with well-differentiated endometrioid adenocarcinoma who request fertility preservation?
CQ37 :What treatments are recommended for recurrent cases of well-differentiated endometrioid adenocarcinoma after fertility preservation therapy?
CQ38 :What are the adverse effects of progesterone therapy and their associated risk factors?
CQ39 :Is induction of ovulation safe in fertility-preserved patients?
CQ40 :What intervals are recommended for follow-up after fertility-preserving treatment? What examinations and investigations should be performed?

Chapter 7 Atypical Endometrial Hyperplasia

Overview
CQ41 :If fertility-preserving treatment is to be performed for atypical endometrial hyperplasia:

(1)Is progesterone therapy useful?
(2)What intervals are recommended for follow-up, and what examinations and investigations should be performed?

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