治療ガイドライン

子宮体がん治療ガイドライン2013年版(英語版):(金原出版)

子宮頸癌治療ガイドライン 2011年版

日本癌治療学会【International Journal of Clinical Oncology (IJCO)】掲載論文内容 (PDF/294KB)

目次

Chapter 1 Overvi of guidelines

Chapter 2 Initial treatment for endometrial cancer (including histologic variant type)

Overview
CQ01 :Which surgical techniques for hysterectomy are recommended for patients considered to be stage I preoperatively?
CQ02 :Which surgical hysterectomy techniques are recommended for patients considered to be stage II?
CQ03 :What are the benefits of pelvic lymphadenectomy?
CQ04 :What are the benefits of para-aortic lymphadenectomy (biopsy)?
CQ05 :Is omentectomy necessary?
CQ06 :Is ovarian preservation possible?
CQ07 :What surgical technique is recommended for serous adenocarcinoma and clear-cell adenocarcinoma?
CQ08 :Is an inguinal lymph node biopsy noted in the surgical staging guidelines necessary?
CQ09:What is a significance of preoperative diagnostic imaging?
CQ10:Is intraoperative frozen-section diagnosis useful to determine the optimal operative method?
CQ11:Should intraoperative frozen-section diagnosis be performed to detect lymph node metastases?
CQ12:Can lymphadenectomy be omitted if a sentinel node biopsy is performed?
CQ13:Should peritoneal cytology be conducted on the occasion of surgery?
CQ14:Can laparoscopic surgery become a standard surgical technique?
CQ15:How should patients who are confirmed to be endometrial cancer after hysterectomy be treated?
CQ16:What is the indication for the definitive radiation therapy?

Chapter 3 Postoperative adjuvant therapy for endometrial cancer (including histologic variant type)

Overview
CQ17 :What are the indications and drugs recommended for postoperative chemotherapy?
CQ18 :Is hormone therapy effective as a postoperative adjuvant therapy?
CQ19:What are the indications for postoperative whole-pelvis external-beam irradiation?
CQ20 :What are the indications for postoperative irradiation of the para-aortic lymph node region and whole abdomen?

Chapter 4 Post-treatment surveillance for endometrial cancer

Overview

CQ21 :What intervals are recommended for post-treatment surveillance?
CQ22 :Should pelvic examinations and vaginal vault smears be performed in post-treatment follow-up?
CQ23 :Should serum tumor markers be measured in post-treatment follow-up?
CQ24 :Should diagnostic imaging be performed in post-treatment follow-up?
CQ25 :Is hormone replacement therapy recommended after treatment?

Chapter 5 Treatment for advanced or recurrent endometrial cancer

Overview
CQ26 :What is the indication for surgery for clinical stages III and IV?
CQ27 :Should neoadjuvant chemotherapy or preoperative radiation therapy be conducted for advanced cancer?
CQ28 :What are the indications for surgery for recurrent cancer?
CQ29 :Should chemotherapy be conducted for advanced cancer of imperfect resection and recurrent cancer?
CQ30 :Should radiation therapy be conducted for recurrent and inoperable advanced cancer?
CQ31 :Should hormone therapy be conducted for advanced and recurrent cancer?

Chapter 6 Fertility-sparing therapy

Overview
CQ32 :When patients with atypical endometrial hyperplasia desire for fertility preservation, is progesterone therapy recommended?
CQ33 :When patients with endometrioid adenocarcinoma (corresponding to G1) desire for fertility preservation, is progesterone therapy recommended?
CQ34 :What are suitable follow-up periods and examinations?
CQ35 :What treatments are recommended for patients with recurrence after fertility preservation therapy?
CQ36 :Is ovulation induction permissible in patients after fertility preservation therapy?

Chapter 7 Treatment of uterine carcinosarcoma and uterine sarcoma

Overview
CQ37 :What surgical techniques are recommended for uterine carcinosarcoma?
CQ38 :What postoperative adjuvant therapy is recommended for uterine carcinosarcoma?
CQ39 :What treatments are recommended for advanced and recurrent uterine carcinosarcoma?
CQ40 :What surgical techniques and postoperative adjuvant therapy are recommended for uterine leiomyosarcoma?
CQ41 :What surgical techniques and postoperative adjuvant therapy are recommended for endometrial stromal sarcoma (ESS)?
CQ42 :What treatments are recommended for unresectable or recurrent ESS/leiomyosarcoma?

Chapter 8 Treatment of trophoblastic disease

Overview
CQ43 :What chemotherapy is recommended for an invasive mole, clinical invasive mole, or post-molar persistent hCG?
CQ44 :What chemotherapy is recommended for choriocarcinoma?
CQ45 :What are the indications for surgery for choriocarcinoma?
CQ46 :What are the indications for radiation therapy for choriocarcinoma?
CQ47 :What treatments are recommended for cases with placental site trophoblastic disease (PSTT) or epithelioid trophoblastic tumor (ETT)?
CQ48 :How should patients with persistent low-positive hCG be treated?

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